Upconversion-bismuth Nanosystem as Theranostic Agent for NIR Laser-driven Chemo-photothermal Therapy
نویسندگان
چکیده
设计并åæäºä¸ç§ç¨äºè¿çº¢å¤å 驱å¨çåå¦âå çæ²»ççä¸è½¬æ¢âé纳米ä½ç³»è¯çåï¼UBDAsï¼ï¼å ¶å ·æåºè²çå ç转æ¢è½åï¼28.5%ï¼åè¯å¥½ççç©ç¸å®¹æ§ãåæ¶ï¼å¨980 nmè¿çº¢å¤å çæ¿åä¸ï¼UBDAsè½å¤åå°ç´«å¤/å¯è§å ï¼ç¨äºä¿è¿å æåå¶æ°®è¯å¨ä»åä¸çè¿ç»æ转â翻转è¿å¨ï¼ä»èå®ç°è¯ç©çå¯æ§éæ¾ï¼ä¸å©ç¨è¿çº¢å¤å æ¿åè½å¤ææé¿å ä¼ ç»ç´«å¤å 对çç©ç»ç»çå¯ä½ç¨ãå çå®éªè¡¨æï¼UBDAsæå纳米ä½ç³»å¨980 nmæ¿å ç §å°ä¸å ·æè¯å¥½çå çæåºãæ¤å¤ï¼å«æTm3+åBiå ç´ çUBDAsææç¨äºä¸è½¬æ¢åå æååXå°çº¿è®¡ç®æºæå±æåï¼è¿èå®ç°å模æåä»å¯¼ä¸åä¸è¿çº¢å¤å æ¿åçççåå¦çæ³åå ççæ³ã该ç 究ç»æ为è¯æåååå¢å¼ºæè¿ç¤æ²»çç综åç 究æä¾äºæ°çæè·¯ã
منابع مشابه
Mn2+-coordinated PDA@DOX/PLGA nanoparticles as a smart theranostic agent for synergistic chemo-photothermal tumor therapy
Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are of great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn2+-coordinated doxorubicin (DOX)-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles as a platform for synergistic chemo-photothermal tumor therapy. DOX-loaded PLGA (DOX/PLGA) nanopa...
متن کاملMesoporous Magnetic Gold “Nanoclusters” as Theranostic Carrier for Chemo-Photothermal Co-therapy of Breast Cancer
Photothermal therapy (PTT) is proved to be an efficient manner for superficial tumor therapy in preclinical studying. The tumor suppression of chemotherapy can be enhanced by combining with PTT. In this study, we reported a mesoporous magnetic gold "nanoclusters" (MMGNCs) structure as theranostic carrier for chemo-photothermal co-therapy. MMGNCs were successfully prepared and they exhibited eff...
متن کاملNIR-Laser-Controlled Drug Release from DOX/IR-780-Loaded Temperature-Sensitive-Liposomes for Chemo-Photothermal Synergistic Tumor Therapy
NIR laser-induced photothermal therapy (PTT) through near-infrared agents has demonstrated the great potential in solid tumor ablation. However, the nonuniform heat distribution over tumors from PTT makes it insufficient to kill all tumor cells, resulting in tumor recurrence and inferior outcomes. To improve the tumor treatment efficacy, it is highly desirable to develop the combinational treat...
متن کاملBiocompatible astaxanthin as a novel marine-oriented agent for dual chemo-photothermal therapy
The photothermal effect of a marine-oriented xanthophyll carotenoid, astaxanthin (AXT), was characterized based on its potential absorption of visible laser light and conversion of optical light energy into heat for thermal treatment. As an antioxidant and anticancer agent, AXT extracted from marine material can be utilized for photothermal therapy due to its strong light absorption. The curren...
متن کاملNovel Cs-Based Upconversion Nanoparticles as Dual-Modal CT and UCL Imaging Agents for Chemo-Photothermal Synergistic Therapy
Lanthanide-based contrast agents have attracted increasing attention for their unique properties and potential applications in cancer theranostics. To date, many of these agents have been studied extensively in cells and small animal models. However, performance of these theranostic nanoparticles requires further improvement. In this study, a novel CsLu2F7:Yb,Er,Tm-based visual therapeutic plat...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chinese Journal of Luminescence
سال: 2022
ISSN: ['1000-7032']
DOI: https://doi.org/10.37188/cjl.20220142